Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26438902 | 1.00 | PARG (0.53) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26438900 | 0.87 | PARP1 (0.49) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6975873 | 0.83 | PARP1 (0.52) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6978855 | 0.83 | KDM4E (0.52) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17786594 | 0.83 | PARG (0.52) | PARGPARP1TYMSELANEKDM4E | |
| SCHEMBL13561497 | 0.81 | TYMS (0.53) | PARGCYP1A2TYMSUSP2ALDH1A1 | |
| SCHEMBL11376113 | 0.80 | PARG (0.50) | PARGPARP1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29535139 | 0.80 | KDM4E (0.66) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7263029 | 0.80 | KDM4E (0.66) | PARGTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2614349 | 0.78 | KDM4E (0.62) | PARP1KDM4EALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174899-B | Application of light-promoted Minisci C-H alkylation reaction in preparation of alkyl-substituted azacycle | 南开大学 | 2023-01-17 | — | — | CN | disclosed |