Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884695 | 1.00 | MAPT (0.36) | MAPTMAPK1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL23884801 | 0.90 | MEN1 (0.33) | MAPTCYP2C19CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL30177229 | 0.90 | MEN1 (0.33) | MAPTCYP2C19CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL23884843 | 0.90 | CYP1A2 (0.36) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL25718876 | 0.90 | CYP1A2 (0.36) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL25718878 | 0.90 | CYP1A2 (0.36) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21957923 | 0.88 | CYP1A2 (0.35) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21958045 | 0.88 | CYP1A2 (0.35) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21957919 | 0.88 | CYP1A2 (0.35) | CYP2C19CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23884812 | 0.88 | KMT2A (0.41) | MAPTMAPK1CYP2C19KMT2AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126832-A1 | MODULATORS OF HEMOGLOBIN | Global Blood Therapeutics, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |