Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 9/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 5/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL22542610 | 0.87 | PRMT1 (0.54) | PRMT1PRMT5PRMT8BLMMLNR | |
| Iodide SCHEMBL22542611 | 0.84 | MEN1 (0.49) | PRMT1BLMS100A4MAPTMEN1 | |
| SCHEMBL22560153 | 0.83 | MEN1 (0.50) | PRMT1BLMS100A4MAPTMEN1 | |
| Iodide SCHEMBL22542614 | 0.82 | PRMT1 (0.53) | PRMT1BLMS100A4MAPTMEN1 | |
| Iodide SCHEMBL22542615 | 0.82 | PRMT1 (0.53) | PRMT1BLMS100A4MAPTMEN1 | |
| Iodide SCHEMBL22542623 | 0.81 | MAPT (0.52) | PRMT1PRMT5PRMT8BLMS100A4 | |
| Iodide SCHEMBL22542622 | 0.81 | MAPT (0.52) | PRMT1PRMT5PRMT8BLMS100A4 | |
| SCHEMBL24446420 | 0.80 | MAPT (0.44) | PRMT1PRMT5PRMT8BLMMLNR | |
| SCHEMBL24437495 | 0.79 | MLNR (0.53) | PRMT1PRMT5PRMT8BLMMLNR | |
| Iodide SCHEMBL22542632 | 0.78 | MEN1 (0.50) | PRMT1BLMS100A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611798-B | PH trigger charge reversible fluorescent probe and application thereof in cell imaging | 齐鲁工业大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115611798-A | pH triggered charge reversible fluorescent probe and application thereof in cell imaging | 齐鲁工业大学 | 2023-01-17 | — | — | CN | disclosed |