Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489910 | 0.86 | MAOB (0.54) | TAAR1MAOB | |
| SCHEMBL26985792 | 0.85 | TAAR1 (0.67) | TAAR1MAOBACHEKDM4E | |
| SCHEMBL465063 | 0.84 | TAAR1 (0.47) | TAAR1MAOBAOC3CHRM2CHRM1 | |
| SCHEMBL27655773 | 0.84 | TAAR1 (0.47) | TAAR1MAOBDRD2AOC3CHRM2 | |
| SCHEMBL146849 | 0.82 | TAAR1 (0.68) | TAAR1MAOBACHEDRD2DRD1 | |
| SCHEMBL30820845 | 0.82 | TAAR1 (0.68) | TAAR1MAOBACHEDRD2DRD1 | |
| SCHEMBL42400 | 0.82 | TAAR1 (1.00) | TAAR1MAOBACHEAOC3CHRM2 | |
| SCHEMBL1445872 | 0.81 | PPARA (0.55) | TAAR1CHRM2CHRM1CHRM3KDM4E | |
| Hydrochloric Acid SCHEMBL21810796 | 0.81 | TAAR1 (0.66) | TAAR1MAOBACHEDRD2DRD1 | |
| Hydrochloric Acid SCHEMBL10917318 | 0.80 | TAAR1 (0.96) | TAAR1MAOBACHEAOC3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |