Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609317 | 0.96 | POLB (0.45) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL31194293 | 0.93 | POLB (0.40) | POLB | |
| SCHEMBL29431598 | 0.92 | POLB (0.52) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL14677239 | 0.92 | POLB (0.52) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL25886471 | 0.92 | POLB (0.40) | POLB | |
| SCHEMBL31081463 | 0.92 | POLB (0.40) | POLB | |
| SCHEMBL25315392 | 0.88 | POLB (0.40) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL30989784 | 0.88 | POLB (0.40) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL15868302 | 0.88 | POLB (0.48) | POLBMEN1NPC1ALDH1A1STAT3 | |
| SCHEMBL23729027 | 0.87 | POLB (0.48) | POLBMEN1NPC1ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143177-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2023-03-08 | — | — | EP | disclosed |
| CN-115702149-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2023-02-14 | — | — | CN | disclosed |