Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.37 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | LITAF | Q99732 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099287 | 0.87 | KRAS (0.55) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL21099374 | 0.85 | KRAS (0.50) | KRASHDAC6GPR119SCN9AHDAC8 | |
| SCHEMBL21099261 | 0.84 | KRAS (0.49) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL30177990 | 0.83 | KRAS (0.42) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL30178172 | 0.82 | KRAS (0.47) | KRASHDAC6TNFLITAF | |
| SCHEMBL21099333 | 0.82 | KRAS (0.78) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL21099629 | 0.82 | KRAS (0.71) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL21099218 | 0.81 | KRAS (0.59) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL21099225 | 0.80 | KRAS (0.68) | KRASHDAC6GPR119TNFLITAF | |
| SCHEMBL21099392 | 0.80 | KRAS (0.65) | KRASHDAC6GPR119TNFLITAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030517-A1 | KRAS G12C INHIBITORS AND USES THEREOF | SUZHOU ZANRONG PHARMA LIMITED (CN) | 2023-03-09 | — | — | WO | disclosed |