Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 17/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870719 | 1.00 | GNRHR (0.38) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL28645644 | 0.91 | GNRHR (0.37) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL19873999 | 0.91 | GNRHR (0.35) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL30178426 | 0.91 | GNRHR (0.35) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL30178380 | 0.89 | GNRHR (0.36) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL19874027 | 0.89 | GNRHR (0.36) | GNRHRCYP3A4BRD4PDK2TRPV4 | |
| SCHEMBL19873953 | 0.85 | BRD4 (0.36) | BRD4PDK2TRPV4 | |
| SCHEMBL17870723 | 0.83 | GNRHR (0.41) | GNRHRCYP3A4 | |
| SCHEMBL30178348 | 0.83 | GNRHR (0.41) | GNRHRCYP3A4 | |
| SCHEMBL17870720 | 0.82 | GNRHR (0.41) | GNRHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |