Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 20/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25601652 | 1.00 | TLR9 (0.36) | TLR9TLR7TLR8 | |
| SCHEMBL24838249 | 0.92 | IRAK4 (0.40) | TLR9TLR7TLR8 | |
| SCHEMBL30178612 | 0.91 | TLR9 (0.38) | TLR9TLR7TLR8 | |
| SCHEMBL25601650 | 0.91 | TLR9 (0.38) | TLR9TLR7TLR8 | |
| SCHEMBL24838251 | 0.85 | TLR9 (0.40) | TLR9TLR7TLR8 | |
| SCHEMBL30178976 | 0.84 | TLR9 (0.42) | TLR9TLR7TLR8 | |
| SCHEMBL24837707 | 0.84 | TLR9 (0.42) | TLR9TLR7TLR8 | |
| SCHEMBL23606907 | 0.77 | TLR9 (0.42) | TLR9TLR7TLR8 | |
| SCHEMBL30035937 | 0.76 | — | — | |
| SCHEMBL23579752 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |