Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999946 | 1.00 | KDR (0.49) | KDRMAPKAPK2 | |
| SCHEMBL23999940 | 0.99 | KDR (0.50) | KDRMAPKAPK2 | |
| SCHEMBL30180462 | 0.99 | KDR (0.50) | KDRMAPKAPK2 | |
| SCHEMBL30180416 | 0.97 | KDR (0.50) | KDRMAPKAPK2 | |
| SCHEMBL23999678 | 0.97 | KDR (0.50) | KDRMAPKAPK2 | |
| SCHEMBL23999608 | 0.92 | MAPKAPK2 (0.54) | KDRMAPKAPK2 | |
| SCHEMBL30180645 | 0.92 | MAPKAPK2 (0.54) | KDRMAPKAPK2 | |
| SCHEMBL24004225 | 0.90 | KDR (0.47) | KDRMAPKAPK2 | |
| SCHEMBL30180315 | 0.90 | KDR (0.47) | KDRMAPKAPK2 | |
| SCHEMBL23999679 | 0.90 | DNMT1 (0.43) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426279-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4146666-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |