Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999538 | 1.00 | DNMT1 (0.46) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL24000006 | 0.95 | DNMT1 (0.53) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL25825374 | 0.95 | DNMT1 (0.53) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL23999597 | 0.89 | HTR2C (0.45) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL30180577 | 0.89 | HTR2C (0.45) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL30180285 | 0.87 | KMT2A (0.56) | DNMT1DNMT3ADNMT3LHTR2CHTR2B | |
| SCHEMBL19151414 | 0.87 | KMT2A (0.56) | DNMT1DNMT3ADNMT3LHTR2CHTR2B | |
| SCHEMBL23999805 | 0.85 | KMT2A (0.47) | DNMT1DNMT3ADNMT3LHTR2CHTR2B | |
| SCHEMBL23999441 | 0.85 | MAPT (0.47) | DNMT1DNMT3ADNMT3LAURKAAURKB | |
| SCHEMBL23999600 | 0.85 | DNMT1 (0.49) | DNMT1DNMT3ADNMT3LHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |