Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999349 | 1.00 | MAPT (0.39) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL24000022 | 0.95 | MAPT (0.39) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL30180608 | 0.91 | MAPT (0.42) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999353 | 0.91 | MAPT (0.42) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL30180383 | 0.90 | MAPT (0.49) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999435 | 0.90 | MAPT (0.49) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999752 | 0.86 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL24003965 | 0.86 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999947 | 0.86 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL30180421 | 0.86 | PDPK1 (0.41) | MAPTPOLBTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426279-A1 | AKT3 MODULATORS | Georgiamune Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4146667-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-4146666-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |