Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 10/20 | 0.61 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.53 |
| ▸ | SLC16A8 | O95907 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 3/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182285 | 0.93 | SLC16A3 (0.61) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30182221 | 0.91 | SLC16A3 (0.61) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30181970 | 0.90 | SLC16A3 (0.60) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30182479 | 0.90 | SLC16A3 (0.60) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30182206 | 0.90 | SLC16A3 (0.65) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30181996 | 0.89 | SLC16A3 (0.75) | SLC16A3SLC16A7SLC16A8HTR5APOLB | |
| SCHEMBL30181821 | 0.89 | SLC16A3 (0.63) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL30182145 | 0.88 | SLC16A3 (0.59) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 | |
| SCHEMBL22116525 | 0.87 | SLC16A3 (0.82) | SLC16A3SLC16A7SLC16A8HTR5A | |
| SCHEMBL30182499 | 0.85 | SLC16A3 (0.60) | SLC16A3SLC16A7SLC16A8HTR5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898588-B1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-01-11 | — | — | EP | claimed |