Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891663 | 1.00 | KIT (0.44) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL29803517 | 0.92 | NAMPT (0.46) | KITNAMPTWNT3ADGAT2GRM5 | |
| SCHEMBL24669292 | 0.90 | NAMPT (0.47) | KITNAMPTWNT3ADGAT2GRM5 | |
| SCHEMBL30182806 | 0.90 | NAMPT (0.51) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL24892312 | 0.90 | NAMPT (0.51) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL30182462 | 0.90 | NAMPT (0.51) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL24891657 | 0.90 | NAMPT (0.51) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL30182464 | 0.90 | NAMPT (0.51) | KITNAMPTWNT3ADGAT2PRKAA2 | |
| SCHEMBL24891692 | 0.85 | PRKAA2 (0.37) | KITNAMPTWNT3APRKAA2HDAC1 | |
| SCHEMBL24891715 | 0.85 | NAMPT (0.45) | KITNAMPTWNT3ADGAT2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |