Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIP | P01282 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.42 |
| ▸ | CBLB | Q13191 | 5/20 | 0.39 |
| ▸ | KCNA6 | P17658 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nagelamide E SCHEMBL29489927 | 0.89 | VIP (0.47) | VIPSCN9ASCN3ACBLBKCNA6 | |
| Bromoageliferin SCHEMBL12648889 | 0.88 | CBLB (0.47) | VIPSCN9ASCN3ACBLBKCNA6 | |
| Bromoageliferin SCHEMBL14985474 | 0.88 | VIP (0.59) | VIPSCN9ASCN3ACBLBKCNA6 | |
| SCHEMBL12597859 | 0.75 | VIP (0.54) | VIPSCN9ASCN3ACBLBKCNA6 | |
| SCHEMBL12559790 | 0.75 | VIP (0.54) | VIPSCN9ASCN3ACBLBKCNA6 | |
| SCHEMBL12852200 | 0.75 | VIP (0.54) | VIPSCN9ASCN3ACBLBKCNA6 | |
| SCHEMBL12559784 | 0.74 | SCN9A (0.53) | SCN9ASCN3ACBLBKCNA6KCNA3 | |
| SCHEMBL12852189 | 0.74 | SCN9A (0.53) | SCN9ASCN3ACBLBKCNA6KCNA3 | |
| SCHEMBL12855198 | 0.70 | VIP (0.49) | VIPSCN9ASCN3ACBLBKCNA6 | |
| SCHEMBL14328328 | 0.69 | SCN9A (0.48) | SCN9ASCN3ACBLBKCNA6KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594626-A | Halogen-substituted 1,2,3, 5-tetra-substituted-1H-indole compound and synthesis method and application thereof | 南京工业大学（CN） | 2023-01-13 | — | — | CN | disclosed |