Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.59 |
| ▸ | FPR3 | P25089 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891973 | 1.00 | NAMPT (0.59) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL30182102 | 1.00 | NAMPT (0.59) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL24891789 | 1.00 | NAMPT (0.59) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL21661827 | 0.95 | NAMPT (0.64) | NAMPTMAPTTDP1HDAC1HDAC6 | |
| SCHEMBL30918897 | 0.95 | NAMPT (0.64) | NAMPTMAPTTDP1HDAC1HDAC6 | |
| SCHEMBL24891860 | 0.89 | NAMPT (0.65) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL24670224 | 0.89 | NAMPT (0.65) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL30182478 | 0.88 | NAMPT (0.59) | NAMPTMAPTTDP1HDAC1HDAC6 | |
| SCHEMBL30182282 | 0.88 | NAMPT (0.52) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL24891767 | 0.87 | NAMPT (0.58) | NAMPTMAPTTDP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |