Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30182604

Nc1ccc(OC2CNC2)cc1.Nc1ccc(OC2CNC2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 1/20 0.41
ITGA5 P08648 1/20 0.41
ITGA4 P13612 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23830859 0.88 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL23830909 0.87 PARP10 (0.55)
Trifluoroacetic Acid SCHEMBL27137357 0.86
Trifluoroacetic Acid SCHEMBL23830840 0.86 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL21590734 0.83
SCHEMBL2582519 0.83 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL23830498 0.82 EPHX2 (0.46)
Trifluoroacetic Acid SCHEMBL23830800 0.81 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL23830644 0.80 SLC6A4 (0.48) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL23831006 0.80 GRIN1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287736-A1 NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) 2023-01-19 WO disclosed