Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656336 | 1.00 | KMT2A (0.49) | KMT2AMEN1PDGFRBPDGFRACDK2 | |
| SCHEMBL2891443 | 0.98 | KMT2A (0.51) | KMT2AMEN1PDGFRBPDGFRACDK2 | |
| SCHEMBL30183006 | 0.98 | KMT2A (0.51) | KMT2AMEN1PDGFRBPDGFRACDK2 | |
| SCHEMBL1327028 | 0.96 | KMT2A (0.45) | KMT2AMEN1PDGFRBPDGFRACDK2 | |
| SCHEMBL12615604 | 0.92 | CDK2 (0.46) | KMT2AMEN1PDGFRBPDGFRACDK2 | |
| SCHEMBL3504900 | 0.84 | MAPK1 (0.50) | CDK2IDH1GSK3B | |
| SCHEMBL1641431 | 0.84 | EGFR (0.49) | PDGFRBPDGFRACDK2IDH1CDC7 | |
| SCHEMBL1641429 | 0.84 | EGFR (0.49) | PDGFRBPDGFRACDK2IDH1CDC7 | |
| SCHEMBL12513296 | 0.84 | PIM1 (0.44) | CDK2IDH1CDC7GSK3BFLT3 | |
| SCHEMBL12813940 | 0.82 | POLB (0.47) | CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452965-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023118253-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023017937-A1 | NOVEL INHIBITOR FOR MULTIPLE PROTEIN KINASES | 계명대학교 산학협력단 | 2023-02-16 | — | — | WO | disclosed |