Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875671 | 1.00 | F2 (0.36) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL20649089 | 1.00 | F2 (0.36) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL21875634 | 1.00 | F2 (0.36) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL30183507 | 1.00 | F2 (0.36) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL30183377 | 0.96 | F2 (0.38) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL20649013 | 0.96 | F2 (0.38) | F2F10ATRCSNK2A1MAPKAPK2 | |
| SCHEMBL21875625 | 0.91 | F2 (0.37) | F2F10ATRCSNK2A1 | |
| SCHEMBL30183032 | 0.91 | F2 (0.37) | F2F10ATRCSNK2A1 | |
| SCHEMBL21875670 | 0.91 | F2 (0.37) | F2F10ATRCSNK2A1 | |
| SCHEMBL30183504 | 0.91 | F2 (0.37) | F2F10ATRCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | claimed |
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |