Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.40 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648927 | 1.00 | ACVR2A (0.40) | ACVR2ATGFBR2NPC1RAB9ADYRK1A | |
| SCHEMBL30183431 | 0.90 | KIT (0.41) | NPC1RAB9AKDRATRTTK | |
| SCHEMBL20649043 | 0.90 | KIT (0.41) | NPC1RAB9AKDRATRTTK | |
| SCHEMBL20649010 | 0.89 | ATR (0.40) | KDRATRTTKEIF2AK3 | |
| SCHEMBL30183571 | 0.89 | ATR (0.40) | KDRATRTTKEIF2AK3 | |
| SCHEMBL20649354 | 0.88 | KDR (0.35) | ACVR2ATGFBR2NPC1RAB9ADYRK1A | |
| SCHEMBL30183719 | 0.88 | KDR (0.35) | ACVR2ATGFBR2NPC1RAB9ADYRK1A | |
| SCHEMBL20649062 | 0.88 | KDR (0.44) | NPC1RAB9AKDRATRTTK | |
| SCHEMBL20649021 | 0.88 | MAPKAPK2 (0.41) | KDRCNR1 | |
| SCHEMBL30183145 | 0.88 | KDR (0.44) | NPC1RAB9AKDRATRTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | claimed |
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |