Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875672 | 1.00 | F2 (0.39) | F2F10CSNK2A1DCPSATR | |
| SCHEMBL20649083 | 0.93 | F2 (0.40) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL30183137 | 0.93 | F2 (0.40) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL20649218 | 0.93 | F2 (0.40) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL30183053 | 0.93 | F2 (0.40) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL21954004 | 0.93 | F2 (0.40) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL30183231 | 0.92 | F2 (0.39) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL20649204 | 0.92 | F2 (0.39) | F2F10CSNK2A1ATRHSD11B1 | |
| SCHEMBL20649130 | 0.92 | F2 (0.39) | F2F10CSNK2A1HSD11B1HSD17B1 | |
| SCHEMBL30183240 | 0.92 | F2 (0.39) | F2F10CSNK2A1ATRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | claimed |
| CN-110997678-B | Pyrazoloquinazoline derivatives as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-02-21 | — | — | CN | disclosed |