Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 16/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123471 | 0.94 | TTK (0.46) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL22123006 | 0.94 | TTK (0.46) | TTKPTK6ABL1BCRBRAF | |
| Hydrochloric Acid SCHEMBL30171868 | 0.93 | TTK (0.45) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL22122864 | 0.93 | TTK (0.46) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL22122947 | 0.92 | TTK (0.47) | TTKPTK6ABL1BCRBRAF | |
| Hydrochloric Acid SCHEMBL30171667 | 0.91 | TTK (0.46) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL30183415 | 0.91 | TTK (0.44) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL22123679 | 0.91 | TTK (0.44) | TTKPTK6ABL1BCR | |
| SCHEMBL22123443 | 0.90 | TTK (0.48) | TTKPTK6ABL1BCRBRAF | |
| SCHEMBL22124900 | 0.89 | TTK (0.46) | TTKPTK6ABL1BCRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | claimed |