Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.38 |
| ▸ | TTK | P33981 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 12/20 | 0.33 |
| ▸ | JAK1 | P23458 | 12/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123847 | 1.00 | PTK6 (0.38) | PTK6TTKJAK2JAK1TBK1 | |
| SCHEMBL22124571 | 0.95 | PTK6 (0.38) | PTK6TTKTBK1LCKAURKB | |
| SCHEMBL22123540 | 0.93 | PTK6 (0.36) | PTK6TTKJAK2JAK1LCK | |
| SCHEMBL22123538 | 0.92 | PTK6 (0.38) | PTK6TTKJAK2JAK1LCK | |
| SCHEMBL22125522 | 0.90 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL24870816 | 0.90 | PTK6 (0.41) | PTK6TTKJAK2JAK1LCK | |
| SCHEMBL30172088 | 0.90 | PTK6 (0.41) | PTK6TTKJAK2JAK1LCK | |
| SCHEMBL30171930 | 0.89 | JAK1 (0.35) | PTK6TTKJAK2JAK1 | |
| SCHEMBL22124606 | 0.89 | PTK6 (0.37) | PTK6TTKJAK2JAK1LCK | |
| SCHEMBL22124000 | 0.89 | PTK6 (0.39) | PTK6TTKJAK2JAK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |