SCHEMBL30183658

CC[C@H](C)[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCN)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)(C)S

nearest known ligand 0.47

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	8/20	0.44

▸	NPY2R	P49146	7/20	0.44

▸	NPY5R	Q15761	7/20	0.44

▸	NPY1R	P25929	5/20	0.44

▸	KISS1R	Q969F8	3/20	0.44

▸	MAPK8	P45983	1/20	0.44

▸	MAPK9	P45984	1/20	0.44

▸	MAPK10	P53779	1/20	0.44

▸	KEAP1	Q14145	1/20	0.43

▸	EP300	Q09472	1/20	0.43

▸	HIF1A	Q16665	1/20	0.43

▸	VIPR1	P32241	1/20	0.42

▸	KDM1A	O60341	1/20	0.42

▸	TFPI	P10646	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30183644	0.98	MAPK8 (0.45)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183612	0.97	MAPK8 (0.46)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183794	0.96	NPY2R (0.47)	NPY4RNPY2RNPY5RNPY1RMAPK8
SCHEMBL30183713	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183957	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183411	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183485	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183616	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30870055	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R
SCHEMBL30183703	0.96	MAPK8 (0.48)	NPY4RNPY2RNPY5RNPY1RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4380689-A1	ANTIMICROBIAL PEPTIDOMIMETICS	Basilea Pharmaceutica International AG, Allschwil (CH)	2024-06-12	—	—	EP	claimed
WO-2023012319-A1	ANTIMICROBIAL PEPTIDOMIMETICS	SPEXIS AG (CH)	2023-02-09	—	—	WO	claimed