Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 18/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.51 |
| ▸ | LCK | P06239 | 7/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123379 | 1.00 | PTK6 (0.61) | PTK6AURKBLCKTTK | |
| Hydrochloric Acid SCHEMBL22123489 | 0.99 | PTK6 (0.60) | PTK6AURKBLCKTTK | |
| Hydrochloric Acid SCHEMBL30171826 | 0.99 | PTK6 (0.60) | PTK6AURKBLCKTTK | |
| SCHEMBL22125269 | 0.97 | PTK6 (0.58) | PTK6AURKBLCKTTK | |
| SCHEMBL30177860 | 0.97 | PTK6 (0.58) | PTK6AURKBLCKTTK | |
| SCHEMBL22160883 | 0.94 | PTK6 (0.59) | PTK6AURKBLCKTTK | |
| SCHEMBL22124913 | 0.93 | PTK6 (0.53) | PTK6AURKBLCKTTK | |
| SCHEMBL22153194 | 0.93 | PTK6 (0.53) | PTK6AURKBLCKTTK | |
| SCHEMBL22124976 | 0.93 | PTK6 (0.53) | PTK6AURKBLCKTTK | |
| SCHEMBL30177795 | 0.93 | PTK6 (0.53) | PTK6AURKBLCKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |