Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949952 | 1.00 | MAP4K1 (0.56) | MAP4K1FGFR1FGFR2PIM1KIT | |
| SCHEMBL19950352 | 0.94 | MAP4K1 (0.60) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL19950066 | 0.90 | MAP4K1 (0.68) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL28903704 | 0.90 | MAP4K1 (0.51) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL19950044 | 0.89 | MAP4K1 (0.52) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL31672290 | 0.89 | MAP4K1 (0.52) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL19950362 | 0.89 | MAP4K1 (0.52) | MAP4K1FGFR1FGFR2PIM1KIT | |
| SCHEMBL30183683 | 0.89 | MAP4K1 (0.52) | MAP4K1FGFR1FGFR2PIM1KIT | |
| SCHEMBL30069603 | 0.88 | MAP4K1 (0.60) | MAP4K1FGFR1FGFR2KITFLT3 | |
| SCHEMBL19950152 | 0.88 | MAP4K1 (0.60) | MAP4K1FGFR1FGFR2KITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119558-A1 | PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF | Incyte Corporation (US) | 2023-01-18 | — | — | EP | claimed |