SCHEMBL30184074

SCHEMBL30184074

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 4/20 0.48
▸ GLP1R P43220 5/20 0.48
▸ SCTR P47872 1/20 0.48
▸ F2 P00734 4/20 0.46
▸ CRHR1 P34998 1/20 0.45
▸ CRHR2 Q13324 1/20 0.45
▸ GRPR P30550 1/20 0.45
▸ TFPI P10646 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865080 0.96 F2 (0.49) CALCRGLP1RSCTRF2CRHR1
SCHEMBL30865070 0.96 GLP1R (0.47) CALCRGLP1RSCTRF2GRPR
SCHEMBL30184234 0.93 CALCR (0.49) CALCRGLP1RSCTRGRPR
SCHEMBL30218810 0.92 CALCR (0.48) CALCRGLP1RSCTRF2CRHR1
SCHEMBL34460635 0.90 CALCR (0.55) CALCRGLP1RSCTRF2TFPI
SCHEMBL31622472 0.90 CALCR (0.55) CALCRGLP1RSCTRF2TFPI
SCHEMBL29798070 0.90 F2 (0.55) CALCRGLP1RSCTRF2TFPI
SCHEMBL31622473 0.89 CALCR (0.55) CALCRGLP1RSCTRF2TFPI
SCHEMBL29849560 0.89 F2 (0.52) CALCRGLP1RSCTRF2TFPI
SCHEMBL30184285 0.89 F2 (0.51) CALCRGLP1RSCTRF2TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes DR. MARY MORRIS & ASSOCIATES, LLC (US) 2026-02-17 — — US disclosed
US-20230018324-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF TYPE 1 DIABETES DR. MARY MORRIS & ASSOCIATES, LLC (US) 2023-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes IAPP, GLP1R, SLC5A1 CALCR 384/4885GLP1R 2/4885SCTR 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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