Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.73 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338608 | 1.00 | MAP4K1 (0.73) | MAP4K1ALK | |
| Hydrochloric Acid SCHEMBL25337624 | 0.99 | MAP4K1 (0.72) | MAP4K1ALK | |
| SCHEMBL30183977 | 0.90 | MAP4K1 (0.77) | MAP4K1ALK | |
| SCHEMBL25947572 | 0.90 | ALK (0.63) | MAP4K1ALK | |
| Phosphine SCHEMBL25950644 | 0.88 | ALK (0.60) | MAP4K1ALK | |
| SCHEMBL31315699 | 0.87 | MAP4K1 (0.75) | MAP4K1ALK | |
| SCHEMBL25947722 | 0.87 | MAP4K1 (0.75) | MAP4K1ALK | |
| SCHEMBL25338692 | 0.87 | MAP4K1 (0.70) | MAP4K1ALK | |
| SCHEMBL32685273 | 0.87 | MAP4K1 (0.70) | MAP4K1ALK | |
| Hydrochloric Acid SCHEMBL29172283 | 0.87 | MAP4K1 (0.74) | MAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367123-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | Glenmark Specialty S.A. (CH) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023281417-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | GLENMARK SPECIALTY S.A. (CH) | 2023-01-12 | — | — | WO | disclosed |