Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577945 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL30184080 | 0.95 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL23590783 | 0.95 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL23577793 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL23590514 | 0.84 | IP6K1 (0.41) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL24885176 | 0.84 | KMT2A (0.37) | ALDH1A1MAPTIP6K1MEN1POLB | |
| SCHEMBL24885175 | 0.84 | OPRL1 (0.37) | KDM4EALDH1A1MAPTIP6K1MEN1 | |
| SCHEMBL23577773 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| Hydrochloric Acid SCHEMBL23578246 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL23591052 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |