Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 17/20 | 0.77 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.63 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337664 | 1.00 | MAP4K1 (0.77) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL30183977 | 0.93 | MAP4K1 (0.77) | MAP4K1ALK | |
| SCHEMBL30183987 | 0.89 | MAP4K1 (0.81) | MAP4K1ALK | |
| SCHEMBL25338147 | 0.89 | MAP4K1 (0.81) | MAP4K1ALK | |
| Hydrochloric Acid SCHEMBL25337589 | 0.89 | MAP4K1 (0.80) | MAP4K1ALK | |
| SCHEMBL25339279 | 0.88 | MAP4K1 (0.81) | MAP4K1ALK | |
| SCHEMBL30184199 | 0.88 | MAP4K1 (0.81) | MAP4K1ALK | |
| SCHEMBL30184122 | 0.87 | MAP4K1 (0.80) | MAP4K1ALK | |
| SCHEMBL25338462 | 0.87 | MAP4K1 (0.80) | MAP4K1ALK | |
| SCHEMBL31315699 | 0.87 | MAP4K1 (0.75) | MAP4K1ALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367123-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | Glenmark Specialty S.A. (CH) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023281417-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | GLENMARK SPECIALTY S.A. (CH) | 2023-01-12 | — | — | WO | disclosed |