Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218898 | 1.00 | GAA (0.55) | GAALMNATP53KMT2AMEN1 | |
| SCHEMBL25592374 | 0.83 | HTT (0.56) | LMNAKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL30184289 | 0.83 | HTT (0.56) | LMNAKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL23413329 | 0.76 | GAA (0.60) | GAALMNATP53KMT2AMEN1 | |
| SCHEMBL30097611 | 0.76 | GAA (0.60) | GAALMNATP53KMT2AMEN1 | |
| SCHEMBL259296 | 0.75 | KMT2A (0.80) | GAALMNATP53KMT2AMEN1 | |
| SCHEMBL2064811 | 0.75 | SCN2A (0.70) | GAALMNATP53KMT2AMEN1 | |
| SCHEMBL25210996 | 0.74 | AHR (0.56) | LMNATP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18824684 | 0.74 | CTSA (0.40) | GAALMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25590400 | 0.74 | CLK2 (0.46) | LMNATP53KMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785064-B | Preparation of trisubstituted pyridine derivatives and use thereof as modulators of aromatic hydrocarbon receptors | 成都奥睿药业有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-115785064-A | Preparation of tri-substituted pyridine derivatives and their use as modulators of aromatic hydrocarbon receptors | 成都奥睿药业有限公司 | 2023-03-14 | — | — | CN | disclosed |