Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.78 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.78 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582440 | 1.00 | HDAC6 (0.78) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL5464848 | 0.91 | HDAC6 (0.78) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL30185511 | 0.90 | HDAC6 (0.67) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL30185520 | 0.90 | HDAC6 (0.65) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL28586566 | 0.90 | HDAC6 (0.67) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL6086357 | 0.90 | HDAC6 (0.65) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL28562747 | 0.89 | HDAC6 (0.64) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL30185502 | 0.89 | HDAC6 (0.64) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL30185530 | 0.89 | HDAC6 (0.64) | HDAC6HDAC8HDAC11HDAC1HDAC2 | |
| SCHEMBL28562690 | 0.89 | HDAC6 (0.64) | HDAC6HDAC8HDAC11HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |