Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.70 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.53 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.53 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099594 | 1.00 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL19329781 | 0.87 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22204254 | 0.87 | PIK3CG (0.74) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL19994429 | 0.84 | PIK3CG (0.66) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22204246 | 0.84 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL19994713 | 0.84 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22204261 | 0.83 | PIK3CG (0.75) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22440936 | 0.83 | PIK3CG (0.76) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22204239 | 0.83 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB | |
| SCHEMBL22204241 | 0.83 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3CAPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |