Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.40 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099533 | 1.00 | PIK3CD (0.42) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL30185586 | 1.00 | PIK3CD (0.42) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL29099560 | 0.76 | PIK3CA (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL29099535 | 0.75 | HRH2 (0.36) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL30185591 | 0.75 | HRH2 (0.36) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL29089049 | 0.71 | XIAP (0.42) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL29089047 | 0.71 | XIAP (0.42) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL1785140 | 0.70 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL1785137 | 0.70 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL1789102 | 0.70 | PIK3CD (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |