SCHEMBL3018569

SCHEMBL3018569

CC(C)C1(C(C)C)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12026382 0.72
SCHEMBL10193199 0.67
SCHEMBL2755095 0.65
SCHEMBL7646085 0.65
SCHEMBL12026391 0.64
SCHEMBL2755084 0.64
SCHEMBL1555232 0.62
SCHEMBL18881105 0.60
SCHEMBL12447873 0.59
SCHEMBL11886193 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203021-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
EP-4119555-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME Lg Chem, Ltd. (KR) 2023-01-18 EP disclosed
US-9656974-B2 Oxazine derivatives SHIONOGI & CO., LTD. (JP) 2017-05-23 US disclosed
US-20160159757-A1 OXAZINE DERIVATIVES SHIONOGI & CO (JP) 2016-06-09 US disclosed
EP-2760829-B1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2016-05-18 EP disclosed
US-9290466-B2 Oxazine derivatives SHIONOGI & CO., LTD. (JP) 2016-03-22 US disclosed
US-9249096-B2 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-02-02 US disclosed
EP-2760828-B1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2015-10-21 EP disclosed
US-9120794-B2 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2015-09-01 US disclosed
US-20150166491-A1 OXAZINE DERIVATIVES SHIONOGI & CO (JP) 2015-06-18 US disclosed
US-20130210839-A1 FUSED AMINODIHYDROPYRIMIDINE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2013-08-15 US disclosed
WO-2013049096-A1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-04 WO disclosed
WO-2013048982-A1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-04 WO disclosed
US-20120258961-A1 4-AMINO-1,3-THIAZINE OR OXAZINE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2012-10-11 US disclosed
US-20120245155-A1 FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP SHIONOGI & CO., LTD. (JP) 2012-09-27 US disclosed
US-20120238557-A1 AMINOTHIAZINE OR AMINOOXAZINE DERIVATIVE HAVING AMINO LINKER SHIONOGI & CO., LTD. (JP) 2012-09-20 US disclosed
US-20120015961-A1 ISOTHIOUREA DERIVATIVES OR ISOUREA DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY SHIONOGI & CO., LTD. (JP) 2012-01-19 US disclosed
US-20100190764-A1 Novel compounds GLAXO GROUP LIMITED 2010-07-29 US disclosed
EP-2178823-A1 SPIRO CYCLOPENTANE COMPOUNDS USEFUL AS ANTAGONISTS OF THE H1-RECEPTOR Glaxo Group Limited (GB) 2010-04-28 EP disclosed
WO-2009016084-A1 SPIRO CYCLOPENTANE COMPOUNDS USEFUL AS ANTAGONISTS OF THE H1-RECEPTOR GLAXO GROUP LIMITED (GB) 2009-02-05 WO disclosed