Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.40 |
| ▸ | NPY1R | P25929 | 6/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374559 | 0.94 | PTGS1 (0.43) | NPY4RNPY5RNPY1RNPY2RPTGS1 | |
| SCHEMBL30186416 | 0.92 | IL23R (0.44) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL30186441 | 0.89 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL29674881 | 0.89 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL31370850 | 0.88 | OPRL1 (0.44) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL31411174 | 0.88 | OPRL1 (0.44) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL31127543 | 0.88 | PTGS1 (0.41) | NPY4RNPY5RNPY1RNPY2RPTGS1 | |
| SCHEMBL29774681 | 0.88 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2ROPRL1 | |
| SCHEMBL31000882 | 0.88 | PTGS1 (0.45) | NPY4RNPY5RNPY1RNPY2RPTGS1 | |
| SCHEMBL29372439 | 0.88 | PTGS1 (0.40) | NPY4RNPY5RNPY1RNPY2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165943-A1 | TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION | CHRYSALIS BIOTHERAPEUTICS, INC. | 2023-06-01 | — | — | US | disclosed |
| EP-4132948-A1 | TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION | Chrysalis Biotherapeutics (US) | 2023-02-15 | — | — | EP | disclosed |