Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642470 | 1.00 | MEN1 (0.42) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL19642676 | 0.92 | MEN1 (0.41) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL19642640 | 0.92 | KMT2A (0.44) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL30187436 | 0.92 | KMT2A (0.44) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL30187431 | 0.91 | HPGD (0.44) | MEN1KMT2AMAPTPDE4APDE4B | |
| SCHEMBL19642564 | 0.91 | HPGD (0.44) | MEN1KMT2AMAPTPDE4APDE4B | |
| SCHEMBL19642520 | 0.90 | EGFR (0.47) | PDE4APDE4BPDE4CPDE4DCACNA1H | |
| SCHEMBL30187411 | 0.90 | EGFR (0.47) | PDE4APDE4BPDE4CPDE4DCACNA1H | |
| SCHEMBL30187468 | 0.90 | EGFR (0.47) | PDE4APDE4BPDE4CPDE4DCACNA1H | |
| SCHEMBL30187464 | 0.90 | KDM4E (0.48) | MEN1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-B | 3-oxo-2, 6-diphenyl-2, 3-dihydropyridazine-4-carboxamide | 拜耳医药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |