SCHEMBL30187477

SCHEMBL30187477

COCc1cnc2c(-c3nc4c(C)c(F)c(OCCO)cc4s3)cc(C)cc2n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395446 1.00 F2RL3 (0.50) F2RL3
SCHEMBL30187727 0.92 F2RL3 (0.52) F2RL3
SCHEMBL21379611 0.92 F2RL3 (0.52) F2RL3
SCHEMBL21395467 0.91 F2RL3 (0.47) F2RL3
SCHEMBL30187551 0.91 F2RL3 (0.47) F2RL3
SCHEMBL21379333 0.90 F2RL3 (0.52) F2RL3
SCHEMBL30187652 0.90 F2RL3 (0.52) F2RL3
SCHEMBL21379616 0.89 F2RL3 (0.54) F2RL3
SCHEMBL30187804 0.89 F2RL3 (0.54) F2RL3
SCHEMBL22341842 0.87 F2RL3 (0.51) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed