SCHEMBL30187515

SCHEMBL30187515

COCc1cnc2c(-c3nc4c(C(O)C5CCC5)cc(OC)cc4s3)cc(C)cc2n1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 13/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782586 1.00 F2RL3 (0.50) F2RL3
SCHEMBL30187618 0.97 F2RL3 (0.49) F2RL3
SCHEMBL19783502 0.97 F2RL3 (0.49) F2RL3
SCHEMBL19783351 0.97 F2RL3 (0.51) F2RL3
SCHEMBL30187491 0.97 F2RL3 (0.51) F2RL3
SCHEMBL19783439 0.87 F2RL3 (0.55) F2RL3
SCHEMBL30189656 0.87 F2RL3 (0.55) F2RL3
SCHEMBL30187849 0.86 F2RL3 (0.60) F2RL3
SCHEMBL19783585 0.86 F2RL3 (0.60) F2RL3
SCHEMBL30187505 0.84 F2RL3 (0.53) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed