SCHEMBL30187686

SCHEMBL30187686

COc1cc(CO)c2nc(-c3cc(C)cc4nc(OC)cnc34)sc2c1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783449 1.00 F2RL3 (0.63) F2RL3
SCHEMBL19782663 0.92 F2RL3 (0.61) F2RL3
SCHEMBL30187529 0.92 F2RL3 (0.61) F2RL3
SCHEMBL30187630 0.90 F2RL3 (0.63) F2RL3
SCHEMBL19783179 0.90 F2RL3 (0.63) F2RL3
SCHEMBL30187658 0.89 F2RL3 (0.55) F2RL3
SCHEMBL19783512 0.89 F2RL3 (0.55) F2RL3
SCHEMBL21395756 0.87 F2RL3 (0.80) F2RL3
SCHEMBL30187700 0.87 F2RL3 (0.80) F2RL3
SCHEMBL22341962 0.85 F2RL3 (0.58) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed