SCHEMBL30187705

SCHEMBL30187705

COc1cnc2c(-c3nc4ccc(OC)nc4s3)cc(C)cc2n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782563 1.00 F2RL3 (0.57) F2RL3
SCHEMBL19783199 0.90 F2RL3 (0.72) F2RL3
SCHEMBL30187716 0.90 F2RL3 (0.72) F2RL3
SCHEMBL19783496 0.88 F2RL3 (0.48) F2RL3
SCHEMBL19783230 0.84 F2RL3 (0.56) F2RL3
SCHEMBL30187549 0.84 F2RL3 (0.56) F2RL3
SCHEMBL21396058 0.82 F2RL3 (0.76) F2RL3
SCHEMBL30187816 0.81 F2RL3 (0.56) F2RL3
SCHEMBL19783362 0.81 F2RL3 (0.56) F2RL3
SCHEMBL19782732 0.80 F2RL3 (0.58) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed