Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 16/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741247 | 1.00 | CHRM4 (0.98) | CHRM4CYP1A2KDM4EMAPTUSP2 | |
| Hydrochloric Acid SCHEMBL19741379 | 0.99 | CHRM4 (1.00) | CHRM4CYP1A2KDM4EMAPTUSP2 | |
| Hydrochloric Acid SCHEMBL30193638 | 0.99 | CHRM4 (1.00) | CHRM4CYP1A2KDM4EMAPTUSP2 | |
| SCHEMBL30187885 | 0.87 | CHRM4 (0.80) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| SCHEMBL19741009 | 0.87 | CHRM4 (0.80) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19740895 | 0.86 | CHRM4 (0.83) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30193497 | 0.86 | CHRM4 (0.83) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| SCHEMBL30187701 | 0.85 | CHRM4 (0.98) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| SCHEMBL19740901 | 0.85 | CHRM4 (0.98) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19741338 | 0.84 | CHRM4 (1.00) | CHRM4CYP1A2KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178391-A | Forward allosteric modulators of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-109310668-B | Positive allosteric modulators of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2023-01-24 | — | — | CN | disclosed |