Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 20/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22116814 | 1.00 | SLC16A3 (0.65) | SLC16A3OPRD1HTR6SLC6A3 | |
| SCHEMBL30188045 | 0.90 | SLC16A3 (0.75) | SLC16A3OPRD1HTR6SLC6A3 | |
| SCHEMBL22116625 | 0.90 | SLC16A3 (0.75) | SLC16A3OPRD1HTR6SLC6A3 | |
| SCHEMBL22134727 | 0.84 | SLC16A3 (0.60) | SLC16A3 | |
| SCHEMBL30188121 | 0.84 | SLC16A3 (0.60) | SLC16A3 | |
| SCHEMBL22116655 | 0.83 | SLC16A3 (0.58) | SLC16A3 | |
| SCHEMBL30187817 | 0.83 | SLC16A3 (0.58) | SLC16A3 | |
| SCHEMBL22116541 | 0.82 | SLC16A3 (0.82) | SLC16A3OPRD1HTR6SLC6A3 | |
| SCHEMBL30188310 | 0.82 | SLC16A3 (0.82) | SLC16A3OPRD1HTR6SLC6A3 | |
| SCHEMBL22116627 | 0.81 | SLC16A3 (0.63) | SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351570-B2 | Disubstituted alkyne derivatives | MERCK PATENT GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351570-B2 | Disubstituted alkyne derivatives | BRCA1, MYC, PCNA | SLC16A3 3198/4885OPRD1 4628/4885HTR6 3513/4885 |
| US-20230052586-A1 | DISUBSTITUTED ALKYNE DERIVATIVES | BRCA1, MYC, PCNA | SLC16A3 3198/4885OPRD1 4628/4885HTR6 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.