Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19948048 | 1.00 | KRAS (0.55) | KRAS | |
| SCHEMBL19637087 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL30188788 | 0.92 | KRAS (0.66) | KRAS | |
| SCHEMBL22994740 | 0.89 | KRAS (0.62) | KRAS | |
| SCHEMBL19948236 | 0.88 | KRAS (0.49) | KRAS | |
| SCHEMBL19617239 | 0.88 | KRAS (0.42) | KRAS | |
| SCHEMBL19617603 | 0.87 | KRAS (0.46) | KRAS | |
| SCHEMBL30188736 | 0.87 | KRAS (0.46) | KRAS | |
| SCHEMBL19617732 | 0.87 | TLR9 (0.40) | KRAS | |
| SCHEMBL19959170 | 0.85 | KRAS (0.68) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |