Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637273 | 1.00 | KRAS (0.73) | KRAS | |
| SCHEMBL19636782 | 0.97 | KRAS (0.73) | KRAS | |
| SCHEMBL19637068 | 0.94 | KRAS (0.72) | KRAS | |
| SCHEMBL30189133 | 0.94 | KRAS (0.72) | KRAS | |
| SCHEMBL19637211 | 0.94 | KRAS (0.72) | KRAS | |
| SCHEMBL19617378 | 0.94 | KRAS (0.72) | KRAS | |
| SCHEMBL19637304 | 0.93 | KRAS (0.74) | KRAS | |
| SCHEMBL19636797 | 0.93 | KRAS (0.75) | KRAS | |
| SCHEMBL19964334 | 0.92 | KRAS (0.73) | KRAS | |
| SCHEMBL19617431 | 0.90 | KRAS (0.59) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |