SCHEMBL30189385

SCHEMBL30189385

Brc1cccnc1-c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
LMNA P02545 3/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
NPC1 O15118 6/20 0.46
TP53 P04637 4/20 0.46
RAB9A P51151 4/20 0.46
ALOX15 P16050 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
HTT P42858 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4612674 1.00 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Pyridine SCHEMBL28835501 0.92 CYP2A6 (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4613671 0.88 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
Cyclohexene SCHEMBL29031319 0.88 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL12471328 0.83 KDM4E (0.53) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7772699 0.81 CDC25B (0.46) KDM4ECYP1A2BLMNPC1TP53
SCHEMBL29666462 0.81 CDC25B (0.46) KDM4ECYP1A2BLMNPC1TP53
SCHEMBL9641308 0.80 KDM4E (0.49) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1031923 0.79 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2138821 0.79 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717231-B AIE active force-induced light five-membered six-membered heterocyclic platinum complex, and preparation method and application thereof 海南师范大学 2023-12-15 CN claimed
CN-114940762-B Polymer, preparation method thereof, polymer electrolyte and lithium ion battery 深圳市贝特瑞新能源技术研究院有限公司 2023-06-06 CN claimed
CN-115636890-A Iron catalyst for selective polymerization of conjugated diolefins with 1,2/3,4 and application thereof 宁波大学 2023-01-24 CN claimed
CN-113717231-B AIE active force-induced light five-membered six-membered heterocyclic platinum complex, and preparation method and application thereof 海南师范大学 2023-12-15 CN disclosed
CN-116396286-A Electron transport material, organic electroluminescent device and device preparation method thereof 安庆飞凯新材料有限公司 2023-07-07 CN disclosed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US disclosed
CN-115636890-A Iron catalyst for selective polymerization of conjugated diolefins with 1,2/3,4 and application thereof 宁波大学 2023-01-24 CN disclosed