SCHEMBL30189573

SCHEMBL30189573

COC(=O)COc1cc2sc(-c3cc(C)cc4nc(OC)cnc34)nc2c(Cl)c1F

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21379524 1.00 F2RL3 (0.50) F2RL3
SCHEMBL30189759 0.92 F2RL3 (0.51) F2RL3
SCHEMBL19783375 0.92 F2RL3 (0.51) F2RL3
SCHEMBL21379436 0.91 F2RL3 (0.53) F2RL3
SCHEMBL21379455 0.90 F2RL3 (0.47) F2RL3
SCHEMBL21395770 0.88 F2RL3 (0.59) F2RL3
SCHEMBL30187579 0.88 F2RL3 (0.59) F2RL3
SCHEMBL21379684 0.88 F2RL3 (0.52) F2RL3
SCHEMBL30187594 0.87 F2RL3 (0.52) F2RL3
SCHEMBL19783719 0.87 F2RL3 (0.52) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed