SCHEMBL30189640

SCHEMBL30189640

COCc1cnc2c(-c3nc4c(Cl)cc(OCCNS(=O)(=O)c5ccc(F)cc5)cc4s3)cc(C)cc2n1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 9/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783276 1.00 F2RL3 (0.75) F2RL3
SCHEMBL19782546 0.93 F2RL3 (0.85) F2RL3
SCHEMBL30187636 0.93 F2RL3 (0.85) F2RL3
SCHEMBL19783304 0.93 F2RL3 (0.87) F2RL3
SCHEMBL30189956 0.93 F2RL3 (0.87) F2RL3
SCHEMBL30189783 0.92 F2RL3 (0.74) F2RL3
SCHEMBL19783411 0.92 F2RL3 (0.74) F2RL3
SCHEMBL19782859 0.91 F2RL3 (0.75) F2RL3
SCHEMBL30189913 0.91 F2RL3 (0.75) F2RL3
SCHEMBL19783162 0.90 F2RL3 (0.72) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed