SCHEMBL30189900

SCHEMBL30189900

COCc1cnc2c(-c3nc4c(C)cc(O[Si](C)(C)C(C)(C)C)cc4s3)cc(C)cc2n1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 14/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783382 1.00 F2RL3 (0.57) F2RL3
SCHEMBL30187729 0.87 F2RL3 (0.68) F2RL3
SCHEMBL21395599 0.87 F2RL3 (0.68) F2RL3
SCHEMBL19782635 0.85 F2RL3 (0.64) F2RL3
SCHEMBL19783338 0.84 F2RL3 (0.59) F2RL3
SCHEMBL22342075 0.84 F2RL3 (0.57) F2RL3
SCHEMBL19783126 0.82 F2RL3 (0.66) F2RL3
SCHEMBL21379330 0.82 F2RL3 (0.71) F2RL3
SCHEMBL21379401 0.82 F2RL3 (0.76) F2RL3
SCHEMBL19783117 0.81 F2RL3 (0.57) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed