SCHEMBL30189928

SCHEMBL30189928

Cc1cc(-c2cc3cc(O[Si](C)(C)C(C)(C)C)c(F)c([Si](C)(C)C)c3o2)c2ncc(OC(F)F)nc2c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 18/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21379390 1.00 F2RL3 (0.57) F2RL3
SCHEMBL30189935 0.81 F2RL3 (0.57) F2RL3
SCHEMBL19783343 0.81 F2RL3 (0.57) F2RL3
SCHEMBL21379461 0.79 F2RL3 (0.70) F2RL3
SCHEMBL21379639 0.78 F2RL3 (0.79) F2RL3
SCHEMBL30189745 0.74 F2RL3 (0.53) F2RL3
SCHEMBL19783175 0.74 F2RL3 (0.53) F2RL3
SCHEMBL19782515 0.73 F2RL3 (1.00) F2RL3
SCHEMBL19783317 0.72 F2RL3 (0.77) F2RL3
SCHEMBL30189875 0.72 F2RL3 (0.77) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed