SCHEMBL30189945

SCHEMBL30189945

Cc1cc(-c2nc3c(Cl)c(F)c(O)cc3s2)c2ncc(OC(F)F)nc2c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 19/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782746 1.00 F2RL3 (0.67) F2RL3
SCHEMBL19782759 0.89 F2RL3 (0.57) F2RL3
SCHEMBL30189701 0.89 F2RL3 (0.57) F2RL3
SCHEMBL30189858 0.86 F2RL3 (0.61) F2RL3
SCHEMBL19783675 0.86 F2RL3 (0.61) F2RL3
SCHEMBL19782424 0.83 F2RL3 (0.68) F2RL3
SCHEMBL21395493 0.83 F2RL3 (0.76) F2RL3
SCHEMBL30187801 0.83 F2RL3 (0.48) F2RL3
SCHEMBL21379640 0.83 F2RL3 (0.48) F2RL3
SCHEMBL21395420 0.80 F2RL3 (0.77) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed